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Research Article | | Volume 12 Issue 2 (October-December, 2023) | Pages 44 - 48

Antimicrobial Activity of Hydrophilic Sealants incorporated with Green Synthesized Silver nanoparticles-An invitro Study

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1
Department of Public Health Dentistry Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Tamil Nadu 600077, India.
2
Department of Pedodontic and Preventive Dentistry Saveetha Dental College and Hospitals, Saveetha Institute of Medica and Technical Sciences, Saveetha University, Tamil Nadu 600077, India.
3
Department of Pharmacology Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Tamil Nadu 600077, India.
Under a Creative Commons license
Open Access
Received
Sept. 21, 2023
Accepted
Dec. 11, 2023
Published
Dec. 23, 2023

Abstract

Background: Dental caries formation is highly prevented by applying pit and fissure sealant but was associated with microleakage and secondary caries formation. Aim and Objectives: To synthesize novel pit and fissure sealant with green synthesized silver nanoparticles and evaluation of antibacterial activity against Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, and Candida albicans. Materials and Methods: Green synthesis of silver nanoparticles was done using beetroot, characterized using FTIR (Fourier transform infrared), EDAX (Energy Dispersive X-ray Analysis), and Scanned Electron Microscope Analysis. A novel pit and fissure sealant was made by incorporating synthesized Ag nanoparticles and hydrophilic nature from Ultra seal XT Hydro. Using amoxicillin as a control, an agar well diffusion method was used to conduct an antimicrobial test for a new sealant against Staphylococcus aureus, Streptococcus mutants, Enterococcus faecalis, and Candida albicans in Muller Hinton Agar \((n=3)\) for each organism. Result: Zone of inhibition was measured, showing statistically significant antimicrobial activity against Streptococcus mutans with the ZOI value \(21mm \pm 2mm\) at \(100\mu l\) concentration of Ag nanoparticles in sealant material. Conclusion: Novel Hydrophilic pit and fissure sealant with Ag nanoparticles are potentially antibacterial against the cariogenic microorganism. Thus, it can be utilized for the better efficiency of topical pit and fissure sealant preventive therapy.

Keywords
Hydrophilic sealant; Pit and fissure sealant; Antimicrobial additives.
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