Guide for Authors

Submission Guidelines


1.      Before You Submit:


  • Familiarize yourself with the Aims & Scope to determine if your manuscript aligns with the journal's focus.

  • Ensure that ethical considerations, copyright, and author guidelines have been thoroughly addressed.

  • Confirm that all listed authors have endorsed the manuscript and are familiar with the Instructions for Authors.

  • Consider adding an optional biography to enhance your submission.


2.      Overview of Manuscript Submissions:


2.1 Types of Publications:


2.1.1 Article: Original research manuscripts reporting scientifically sound experiments with new information. Structure: Abstract, Keywords, Introduction, Materials and Methods, Results, Discussion, and optional Conclusions. Suggested minimum word count: 4000 words.


2.1.2 Review: Comprehensive analysis of existing literature, identifying gaps, and providing recommendations. No new, unpublished data should be presented. Structure: Abstract, Keywords, Introduction, Relevant Sections, Discussion, Conclusions, and Future Directions. Suggested minimum word count: 4000 words.


2.1.3 Brief Reports: Short, observational studies with preliminary or complete results. Detailed Materials and Methods to ensure reproducibility. Structure similar to an article. Suggested minimum word count: 2500 words.


2.1.4 Case Report: Detailed information on symptoms, diagnosis, treatment, and outcomes of an individual patient. Structure: Abstract, Keywords, Introduction, Detailed Case Description, Discussion, and Conclusions. Suggested minimum word count: 2500 words.


2.1.5 Communication: Short articles presenting groundbreaking preliminary results or significant findings. Structure similar to an article. Suggested minimum word count: 2000 words.


2.1.6 Conference Report: Overview of a conference, seminar, or meeting events. Structure: Abstract, Keywords, Introduction, Conference Sections, and Concluding Remarks. Suggested minimum word count: 2500 words.


2.1.7 Editorial: Non-peer-reviewed texts announcing new sections, Editor-in-Chief changes, Special Issues, or invited editorials. Brief introduction of the Editorial's purpose and aim. Should not include unpublished or original data. Include Conflict of Interest statement.


2.1.8 Hypothesis: Introduces a new hypothesis or theory. Presents a novel interpretation of recent data. Testable hypothesis within the current knowledge framework. Structure: Abstract, Keywords, Introduction, Relevant Sections, and Concluding Remarks. Suggested minimum word count: 4000 words.


2.1.9 Opinion: Short articles reflecting the author's viewpoints on a subject, technique, or recent findings. Structure similar to a review but shorter. Suggested minimum word count: 2000 words.


2.1.10 Perspective: Usually an invited article showcasing current developments in a specific field. Emphasizes future directions with a personal assessment. Structure similar to a review. Suggested minimum word count: 3500 words.


2.1.11 Protocol: Detailed step-by-step description of a proven and reproducible method. Accompanies a previously published article using the method. Structure: Abstract, Keywords, Introduction, Experimental Design, Materials and Equipment, Detailed Procedure, and Expected Results. Suggested minimum word count: 4000 words.


2.1.12 Registered Report: Peer-reviewed before research and data collection. Provisionally accepted based on scientific rigor, soundness, and importance. Data collection starts after provisional acceptance.


2.1.13 Technical Note: Brief articles focused on a new technique, method, or procedure. Describes important modifications or unique applications. Structure: Abstract, Keywords, Introduction, Materials and Methods, Results, Discussion, and Conclusions. Suggested minimum word count: 3000 words.


2.2 Submission Procedure


For the submission of manuscripts to the Journal of Pioneering Medical Sciences, please utilize the Scholar Manuscript online platform. The submitting author, usually the corresponding author, bears responsibility for the manuscript throughout the submission and peer-review process. It is imperative that the submitting author ensures the inclusion of all eligible co-authors in the author list, confirming their awareness and approval of the submitted manuscript. To initiate the submission process, register and log in to Scholar Manuscript. Once registered, co-authors can access manuscript details within the submission system by registering and logging in with the provided email address used during manuscript submission.


2.2.1 Free-Format Submission


Journal of Pioneering Medical Sciences supports free-format submission:


  • There are no stringent formatting requirements; however, all manuscripts must include essential sections: Author Information, Abstract, Keywords, Introduction, Materials & Methods, Results, Conclusions, Figures and Tables with Captions, Funding Information, Author Contributions, Conflict of Interest, and other Ethics Statements.
  • References may adopt any style, as long as consistent formatting is maintained. It is crucial to include author(s) name(s), journal or book title, article or chapter title (if applicable), year of publication, volume and issue (if applicable), and pagination. While Digital Object Identifier (DOI) numbers are not obligatory, their inclusion is highly encouraged. Recommended bibliography software packages include EndNote, Zotero, Mendeley, and Reference Manager.

  • During the revision stage, you will be prompted to format the manuscript in accordance with the journal guidelines.


2.2.2 Cover Letter Guidelines


Every manuscript submission must be accompanied by a concise cover letter. This letter should succinctly outline the significance of the paper's content, contextualize the findings within existing literature, and elucidate how the manuscript aligns with the journal's scope.


Acknowledgment of any previous submissions of the manuscript to the Journal of Pioneering Medical Sciences is essential. In such cases, providing the previous manuscript ID in the submission system is highly recommended, streamlining the current submission process. Proposed and excluded reviewer names should be submitted within the system, not in the cover letter.


All cover letters must include the following statements:


  1. Confirmation that neither the manuscript nor any parts of its content are under consideration or published in another journal.

  2. Assurance that all authors have endorsed the manuscript and concur with its submission to the specified journal.


2.2.3 Author Identification


Authors are invited to supplement their submission with a brief biography (300–1500 characters). This paragraph should encompass:


  1. Full names of authors and their current positions.

  2. Educational background, specifying institutions and graduation years (degrees obtained).

  3. Work experience details.

  4. Current and past research interests.

  5. Memberships in professional societies and received awards.


2.2.4 Author Affiliation


Authors are required to indicate their current affiliation and the institution where the majority of the research for the manuscript was conducted. While designating the primary affiliation where most research occurred is recommended, authors should verify any contractual agreement requirements with their institution.


Accurate author names and affiliations are crucial, as inaccuracies can lead to attribution issues, incorrect citations, and potential challenges with promotions or funding. After article publication, updates or corrections to the author's address or affiliation may be restricted.


2.2.5 Independent Researcher


If any author is not currently affiliated with a university, institution, or company, or has not been during manuscript development, they should designate themselves as an "Independent Researcher."


2.3 Manuscript Preparation Guidelines


2.3.1 General Considerations Research Manuscripts Structure:


  • Front Matter: Title, Author List, Affiliations, Abstract, Keywords.


  • Research Manuscript Sections: Introduction, Materials and Methods, Results, Discussion, Conclusions (optional).


  • Back Matter: Supplementary Materials, Acknowledgments, Author Contributions, Conflicts of Interest, References.


  • Review Manuscripts Structure: Front matter, literature review sections, and back matter. Utilize the provided template for the front and back matter of review manuscripts. Deviation from the remaining structure is acceptable. Structured reviews and meta-analyses should align with research article structure.


  • Case Reports Structure: Succinct introduction to the medical condition or relevant symptoms.


  • Case presentation: In-depth, de-identified patient demographic and descriptive information, symptoms, diagnosis, treatment, and outcome.


  • Discussion: Context, explanation of treatment decisions.


  • Conclusion: Briefly outline take-home message and lessons learned.


  • Acronyms/Abbreviations/Initialisms: Define upon first appearance in the abstract, main text, and first figure or table. Include the acronym/abbreviation/initialism in parentheses after the full form.


  • Units: Utilize SI Units (International System of Units). Convert Imperial, US customary, and other units to SI units when possible.


  • Accession Numbers: Provide RNA, DNA, and protein sequence accession numbers in the Materials and Methods section.


  • Equations: Use Microsoft Equation Editor or MathType add-on in editable formats. Equations should not be in picture format.


  • Research Data and Supplementary Materials: Publication implies making all associated materials, data, and protocols available to readers. Disclose any restrictions on material or information availability at the submission stage.


  • Preregistration: For preregistered studies or analysis plans, include links in the manuscript. Front Matter Requirements


  • Title: Craft a concise, specific, and pertinent title for your manuscript. Clearly indicate if it involves human or animal trial data, systematic review, meta-analysis, or replication study. When incorporating gene or protein names, use abbreviated forms. Avoid including running titles or heads as they will be removed.

  • Author List and Affiliations: Provide full first and last names of authors, with optional middle name initials. Follow the PubMed/MEDLINE standard format for affiliations, including complete address details. Designate one author as the corresponding author. Authors' email addresses will be displayed on published papers, with the corresponding author responsible for obtaining consent. Equal contributors should be marked with a superscript symbol (†), with a corresponding statement below affiliations.

  • Abstract: Limit the abstract to a maximum of 200 words, encompassing the following:


  1. Contextualize the addressed question and emphasize the study's purpose.

  2. Briefly outline the main methods or treatments, including relevant preregistration numbers and animal details.

  3. Summarize the principal findings.

  4. State the main conclusions or interpretations objectively. Avoid presenting unverified results or overstating conclusions.


  • Keywords: Include three to ten pertinent keywords after the abstract. Opt for terms specific to the article yet reasonably common within the subject discipline. These front matter elements are essential for clarity, adherence to standards, and effective communication of your manuscript's key details. Research Manuscript Sections


  • Introduction: Briefly contextualize the study within a broader framework, emphasizing its significance and purpose. Clearly define the study's aim and specific hypotheses to be tested. Provide a meticulous review of the current state of the research field, citing key publications and addressing controversial hypotheses. Conclude the introduction by highlighting the main goal and key conclusions. Ensure the content remains accessible to scientists beyond the paper's specific topic.

  • Materials and Methods: Offer a detailed description of materials and methods to facilitate replication and extension of published results. Elaborate on new methods and protocols, while succinctly covering established ones with proper citations. Specify software names and versions, indicating the availability of computer code. Include pre-registration codes for transparency.

  • Results: Present a succinct and precise account of experimental results, along with their interpretation and relevant conclusions. Clearly articulate the experimental findings.

  • Discussion: Engage in a thoughtful discussion of results, contextualizing them within the framework of prior studies and working hypotheses. Explore the broader implications of the findings and acknowledge any limitations. Highlight potential directions for future research. This section may be combined with the Results for conciseness.

  • Conclusions: While optional, this section can be added if the discussion is exceptionally lengthy or intricate. Summarize key points and conclusions for clarity.

  • Patents: This optional section may be included if the reported work has resulted in patents. Provide relevant patent information, if applicable. Back Matter


  • Supplementary Materials: Describe any additional materials published online alongside the manuscript, such as figures, tables, videos, or spreadsheets. Clearly label each element with the respective name and title (e.g., Figure S1: title, Table S1: title).


  • Author Contributions: Ensure that each author has significantly contributed to the work and indicate their specific roles. A brief paragraph for research articles with multiple authors, specifying individual contributions, should be provided. Use standardized statements, such as those found at LINK.


  • Funding: Disclose all sources of study funding, indicating grants supporting the research and funds covering publication costs. Clearly state whether the research received external funding or if the authors declare no external funding. Provide accurate details, using standard spellings of funding agency names.


  • Institutional Review Board Statement: Include the Institutional Review Board (IRB) statement and approval number for studies involving humans or animals. Confirm adherence to the Declaration of Helsinki guidelines or provide a detailed justification if ethical review was waived or is not applicable.


  • Informed Consent Statement: For studies involving humans, declare whether informed consent was obtained from all subjects. Clearly state if patient consent was waived, along with the rationale. Specify if not applicable, and confirm written informed consent for publication if applicable.


  • Data Availability Statement: Specify the location of data supporting reported results, including links to publicly archived datasets. Optionally exclude this statement if the study did not report any data.


  • Acknowledgments: Express gratitude for support beyond author contributions or funding, including administrative and technical assistance or material donations.


  • Conflicts of Interest: Declare any personal circumstances or interests that could influence the interpretation of research results. Clearly state conflicts or declare no conflict of interest. Disclose the role of funding sponsors in the research project and decision to publish.


  • References: Number references in order of appearance in the text and list them individually at the manuscript's end. Utilize reference management tools to prevent errors. In-text reference numbers should be in square brackets [ ], placed before punctuation. Citations and references in supplementary files are permitted but must also appear in the main text.


References should be described as follows, depending on the type of work:


  • Journal Articles:

  1. Author 1, A. B., & Author 2, C. D. (Year). Title of the article. Full Journal NameVolume(Issue), page range.


  • Books and Book Chapters:

  1. Author 1, A., & Author 2, B. (Year). Book Title, 3rd ed.; Publisher: Publisher Location, Country, page range.


  1. Author 1, A., & Author 2, B. (Year). Title of the chapter. In Book Title, 2nd ed.; Editor 1, A., & Editor 2, B., Eds.; Publisher: Publisher Location, Country, Volume 3, pages range.


  • Unpublished materials intended for publication:

  1. Author 1, A. B., & Author 2, C. (Year). Title of Unpublished Work (optional). Correspondence Affiliation, City, State, Country. status(manuscript in preparationto be submitted).

  2. Author 1, A. B., & Author 2, C. (Year). Title of Unpublished Work. Full Journal Namephrase indicating stage of publication(submittedacceptedin press).


  • Unpublished materials not intended for publication:

  1. Author 1, A. B. (Affiliation, City, State, Country), Author 2, C. (Affiliation, City, State, Country). Phase describing the material, year. (phase: Personal communication; Private communication; Unpublished work; etc.)


  • Conference Proceedings:

  1. Author 1, A. B., Author 2, C.D., & Author 3, E. F. (Year). Title of Presentation. In Title of the Collected Work(if available), Proceedings of the Name of the Conference, Location of Conference, Country, Date of Conference; Editor 1, Editor 2, Eds. (if available); Publisher: City, Country, Abstract Number (optional), Pagination (optional).


  • Thesis:

  1. Author 1, A. B. (Year). Title of Thesis. Level of Thesis, Degree-Granting University, Location of University.


  • Websites:

  1. Title of Site. Available online: URL (accessed on Day Month Year).
    Unlike published works, websites may change over time or disappear, so we encourage you create an archive of the cited website using a service such as WebCite. Archived websites should be cited using the link provided as follows:

  2. Title of Site. URL (archived on Day Month Year).

3. Preparation of Figures, Schemes, and Tables


3.1 Figures and Schemes Submission:


Submit a single zip archive containing Figures and Schemes during manuscript submission, ensuring a minimum resolution of 1000 pixels width/height or 300 dpi (or higher). Accepted formats include TIFF, JPEG, EPS, and PDF, with preference given to the latter.


Journal of Pioneering Medical Sciences supports the publication of multimedia files within articles or as supplementary materials. For additional details, contact the editorial office.


3.2 Integration into the Main Text:


Insert Figures, Schemes, and Tables close to their initial citation, sequentially numbered (Figure 1, Scheme 1, Figure 2, Scheme 2, Table 1, etc.).


3.3 Title and Caption:


Provide a concise explanatory title and caption for each Figure, Scheme, and Table to enhance clarity and understanding.


3.4 Table Formatting:


Include an explanatory heading for all table columns. For larger tables, consider using smaller fonts to aid copy-editing. Utilize Microsoft Word's Table option for table creation.


3.5 Color Recommendations:


Authors are encouraged to create figures and schemes in color (RGB at 8-bit per channel). There is no additional charge for the publication of full-color graphics.


Adhering to these guidelines ensures seamless integration of visual elements into the manuscript, enhancing the overall quality and comprehension of the content.


4. Supplementary Materials, Data Deposit, and Software Source Code Guidelines


4.1 Research Data Policies:


Journal of Pioneering Medical Sciences is dedicated to fostering open scientific exchange and promoting best practices in data sharing and archiving. Authors are encouraged to share research data, following policies aligned with FAIR Principles.


4.2 Data Availability Statements:


  • Data sharing is encouraged, but ethical, legal, or privacy concerns may restrict it. Authors must clearly state any limitations in the Data Availability Statement.


  • Provide details on data location, including publicly accessible repositories, request-based access, or instances where data sharing is not applicable.


  • When third-party data is used, acknowledge restrictions and provide the necessary permissions.


4.3 Data Citation:


Include comprehensive data citation following the format: [dataset] Authors. Year. Dataset title; Data repository or archive; Version (if any); Persistent identifier (e.g., DOI).


4.4 Computer Code and Software:


  • Release novel computer code via recognized public repositories or as supplementary information.


  • Clearly indicate the name and version of all software used.


4.5 Supplementary Material:


Additional data/files can be submitted as "Supplementary Files" during manuscript submission, aiding the peer-review process. Any file format is acceptable.


4.6 Unpublished Data:


  • Disclose restrictions on data availability during submission. Avoid "Data not shown"; instead, publish all related observations as Supplementary Material.


  • Cite "Unpublished data" or "Personal Communication" in the text and add references in the References section.


4.7 Remote Hosting and Large Data Sets:


  • Deposit large data sets (>60 MB) with specialized service providers, preferably DataCite-enabled repositories.


  • Provide repository name, data set link (URL), and accession number, DOI, or handle number in the paper.


4.8 Deposition of Sequences and Expression Data:


  • Deposit new sequence information in the appropriate database before manuscript submission.


  • Follow guidelines for deposition based on data type (nucleic acid sequences, HTS datasets, microarray data, protein sequences).


4.9 References in Supplementary Files:


Citations and references in Supplementary files are permitted if they also appear in the main text reference list.


5.      Reviewers Recommendations


Authors are encouraged to propose three potential reviewers with expertise relevant to their manuscript. Please provide detailed contact information, ensuring proposed referees are not current collaborators or co-authors within the last three years. Suggested reviewers should represent diverse institutions from the authors and may include Editorial Board members or frequently cited authors.


6.      Extensive English Editing


Authors are responsible for submitting manuscripts in correct English. The APC covers minor English editing by native speakers, excluding extensive editing. Papers requiring substantial edits may be returned, potentially delaying publication. Authors are advised to seek review from English-speaking colleagues or professional editing services before submission.


7.      Preprints and Conference Papers

Journal of Pioneering Medical Sciences accepts preprints, draft versions of papers available online before formal journal submission, even if previously shared. Expanded and high-quality conference papers may be considered as articles, given they meet specific criteria: (1) expanded to research article size; (2) proper citation on the first page; (3) permissions obtained if authors don’t hold copyright; (4) disclosure in the cover letter, stating changes made. Notably, the journal doesn’t publish pilot studies or studies lacking adequate statistical power.


8.      Authorship Criteria:


The Journal of Pioneering Medical Sciences adheres to the guidelines set forth by the International Committee of Medical Journal Editors (ICMJE) for authorship qualification. To be considered an author, individuals must meet the following criteria:


  • Significant contributions to the conception, design, acquisition, analysis, or interpretation of the work.

  • Involvement in drafting the manuscript or critically reviewing it for intellectual content.

  • Granting final approval for the published version.

  • Agreement to be accountable for all aspects, ensuring the accuracy and integrity of the entire work.


Contributors not meeting authorship criteria should be acknowledged in the manuscript's acknowledgments section. Detailed authorship guidance is available through the ICMJE.


9.      Author List Changes:


Any modifications to the author list require approval from all authors, including those removed. The corresponding author serves as the primary contact with the editor, keeping co-authors informed and involving them in significant publication decisions. The Journal reserves the right to verify that all authors meet the specified authorship conditions.


10 Editorial Independence:


10.1 Non-Interference in Editorial Decisions:


The Journal of Pioneering Medical Sciences upholds strict editorial independence and refrains from interfering with editorial decisions. Peer-reviewed articles undergo evaluation by independent editorial boards, ensuring decisions on manuscript acceptance are based solely on:


  • Suitability of chosen reviewers.

  • Adequacy of reviewer comments and author responses.

  • Overall scientific quality of the paper.


10.2 Editors and Editorial Staff as Authors:


Editorial staff or editors are barred from handling their own academic work. Submissions authored by them undergo review by at least two external reviewers. Decisions are made by Editorial Board Members without conflicts of interest. Journal staff play no role in the processing of their own submissions to the Journal of Pioneering Medical Sciences.


11.  Declaration of Conflicts of Interest:


In accordance with The International Committee of Medical Journal Editors, authors are urged to refrain from entering agreements with study sponsors, be they for-profit or non-profit, that impede access to study data or compromise the authors' ability to independently analyze, interpret, and publish manuscripts at their discretion.


11.1 Mandatory Disclosure:


All authors are obligated to divulge any relationships or interests that may unduly influence or bias their work. Potential conflicts encompass both financial interests (e.g., memberships, employment, consultancies, stock ownership, grants, honoraria, funding, paid expert testimonies, and patent-licensing arrangements) and non-financial interests (e.g., personal or professional relationships, affiliations, and beliefs).


11.2 Disclosure Process:


Authors can communicate potential conflicts of interest by email to the managing editor. The corresponding author is responsible for incorporating a concise summary statement in a designated section titled "Conflicts of Interest," positioned just before the reference list in the manuscript. This statement should encompass all disclosed potential conflicts of interest.


11.3 Sample Disclosures:


Conflicts of Interest: Author A has received research grants from Company A. Author B received a speaker honorarium from Company X and holds stocks in Company Y. Author C served as a consultant and expert witness for Company Z. Author D is the inventor of patent X.


11.4 Absence of Conflicts:


If no conflicts exist, authors should expressly state: Conflicts of Interest: The authors declare no conflicts of interest.


12.  Editorial Procedures and Peer-Review Process


12.1 Pre-Check:


Upon submission, the Managing Editor of the Journal of Pioneering Medical Sciences conducts a technical pre-check to evaluate:


  • Overall manuscript suitability for the journal, section, or Special Issue.

  • Manuscript compliance with high-quality research and ethical standards.

  • Adherence to rigorous standards for further review.


The academic editor, such as the Editor-in-Chief, Guest Editor, or Editorial Board member (in cases of conflict or regular submissions with the Editor-in-Chief's approval), is informed and invited to perform an editorial pre-check. This involves assessing the submission's alignment with the journal's scope, scientific soundness, relevance of references, and correctness of methodology. The academic editor may reject the manuscript, request revisions pre-peer-review, or proceed with peer-review, recommending suitable reviewers.


12.2 Peer-Review:


Once past the initial checks, the manuscript is assigned to a minimum of two independent experts for peer-review. The review is single-blind, with reviewers aware of authors' identities. Peer-review comments remain confidential, disclosed only with the reviewer's consent. Experts invited for regular submissions may include Editorial Board Members, Guest Editors, or those suggested by authors, ensuring no recent collaborations or current affiliations with co-authors' institutions.


12.3 Editorial Decision and Revision:


Following peer-review, the academic editor communicates one of the following decisions:


  • Accept after Minor Revisions: Authors perform minor revisions within five days.

  • Reconsider after Major Revisions: Authors provide detailed responses or rebuttals for major revisions. A maximum of two rounds of major revision is standard. Authors resubmit within a suitable timeframe, and the revised version is returned for additional comments.

  • Reject and Encourage Resubmission: If more experiments are needed, authors are encouraged to resubmit after conducting additional research.

  • Reject: Manuscript has serious flaws or lacks original significant contribution. No resubmission offer.


Authors must respond to all reviewer comments in a detailed manner, addressing disagreements clearly.


13.  Author Appeals:


Authors can appeal a rejection within three months, following a "reject and decline resubmission" decision. Appeals, providing detailed justifications and point-by-point responses to reviewers' and/or Editor's comments, are forwarded to a designated Editorial Board Member. The Academic Editor's recommendation is validated by the Editor-in-Chief. Reject decisions at this stage are final and cannot be reversed.


14.  Production and Publication:


Accepted manuscripts undergo professional copy-editing, English editing, proofreading, final corrections, pagination, and are published on the journal's website.


15. Fostering Equity, Diversity, and Inclusion at Journal of Pioneering Medical Sciences


Our commitment to promoting a culture of equity, diversity, and inclusiveness is exemplified through the encouragement given by our Managing Editor to the Editors-in-Chief and Associate Editors in the appointment of diverse and expert Editorial Boards. This commitment extends to our multi-national and inclusive workplace, where we take pride in offering equal opportunities without discrimination based on gender, ethnicity, sexual orientation, age, religion, or socio-economic status. Upholding these principles is paramount for our editors at the Journal of Pioneering Medical Sciences.


16. Resource Identification Initiative


In our pursuit of enhancing the reproducibility of scientific research, we endorse the Resource Identification Initiative. This initiative seeks to assign unique persistent identifiers, known as RRIDs, to vital biological resources such as antibodies, cell lines, model organisms, and tools.


Authors are strongly encouraged to incorporate these RRIDs, provided by the Resource Identification Portal, into the designated section of their manuscripts. To facilitate authors in swiftly identifying the correct identifiers for their materials, a centralized website is available, encompassing all types of resources. Moreover, a 'cite this' button is conveniently located next to each resource, offering a properly formatted citation text that authors can seamlessly include in the methods section of their manuscripts. 


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